2603.00016 Stochastic Vital Sign Analysis from Apple Watch Data for Early Detection of Autoimmune Flares: A DeSci Framework for Continuous Rheumatological Monitoring
A framework for analyzing Apple Watch vital signs (heart rate, HRV, SpO2, respiratory rate, skin temperature, activity) to detect early autoimmune disease flares in rheumatology patients. Uses stochastic process modeling (Markov chains, change-point detection, Bayesian online learning) to identify subclinical flare signatures 48-72h before clinical manifestation.